Chinyorwa ichi chinotarisa pane antimicrobial mechanism yeGemini surchers
Surfactant, iyo inowirirana nemitsara yemukati, inoshanda uye mumiririri. Surfers Surfact Nekuvandudzwa kwenharaunda uye kufambira mberi kweshanduro yenyika
Magungano akajairwa ari "Amphiphilic" mishonga inosanganisira polar hydrophic mapoka uye nonpiris hydrophobic mapoka, uye zvimiro zvavo zvinonyadzisira zvinoratidzwa mumufananidzo 1 (a).
Parizvino, nekuvandudzwa kwekunatswa uye kururamisa muindasitiri yekugadzira, kudiwa kwezvinhu zvekugadzira mune yekugadzira kuri kuwedzera zvishoma nezvishoma, saka zvakakosha kuwana uye kugadzira surfacts nekumusoro kwepamusoro zvinhu uye nezvimiro zvakakosha. Kuwanikwa kweGemini Surchants mabhenekeri aya uye anosangana nezvinodiwa zvekugadzirwa kwemaindasitiri. A yakajairika gemini surfactant ndeyemapoka maviri ehydrophilic (kazhinji ionic kana nonition yacho ne hydrophilic zvivakwa) uye maviri hydrophobic alkyl chaani.
Sezvinoratidzwa mumufananidzo 1 (b), mukusiyana nekunowanzoitika sarfactan surfers Muchidimbu, chimiro cheGemini Surfactant chinogona kunzwisiswa sekuumbwa nekuchenjera kusungwa kwemaviri hydrophic misoro mapoka ezvemamiriro ezvinhu akajairika pamwechete neboka rekubatana.
Chimiro chakakosha cheGemini surfactant chinotungamira kune yayo yepamusoro nzvimbo, iyo inonyanya kukonzerwa ne:
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Gemini Surepants ane yepamusoro (muganho) chiitiko, yakaderera micelle yekunyora myolecent, yakanaka kwazvo, kugona kweiyo uye antibacterial kugona kana uchienzaniswa nemawereji akajairwa. Naizvozvo, kuvandudzwa uye kushandisa kweGemini surapants ndeye kukosha kukuru kwekukura uye kushandiswa kweasurfaers.
Iyo "Amphiphilic chimiro" chemagirazi epasireti anovapa akasiyana-siyana epasi. Sezvinoratidzwa mumufananidzo 1 (C), apo shutera yakajairika inowedzerwa kumvura, boka remusoro rehydrophilic rinowanzo nyungudza mukati memvura mhinduro, uye boka re hydrophobic rinotadzisa kutsvaira kwemvura yemvura. Pasi pemhedzisiro yeaya maviri maitiro, mamorekukadzi mamalecules akafumiswa pagesi-yemvura interface uye anogadzirisa kurongeka kwenguva, nekudaro achideredza kusawirirana kwemvura. Kusiyana nemagungano akajairika, Gemini surfects are "vanonongedza" izvo zvinobatanidza mafambiro epasikiridzo pamwechete kuburikidza nemapoka emvura, ayo anokwanisa kuderedza kwemvura nemvura / mvura yekunetseka zvakanyanya. Mukuwedzera, Gemini Surchersve ane akaderera mimbira yekumanikidza
| Nhanganyaya yeGemini Surepants Muna 1991, mernger uye littau [13] akagadzirira iyo yekutanga bis-alkyl ketjarly nejira rekubatana, uye rakatumidzwa kuti "Gemini Surfantant". Mugore rimwe chetero, zana et al [14] akagadzirira quaternary quaternary quaternary tumoni surfachers kekutanga uye akarongeka akaongorora zvivakwa zveiyi nhare yeQuaternary Apmini Salapants. 1996, vaongorori vakawanda uye vakakurukura pamusoro (muganho) maitiro, maAggregation Profiology uye chikamu cheChikamu cheMihemandi Surapants kana akaiswa pamwedzi akajairwa. Muna 2002, ZANA [15] Kuongorora mhedzisiro yemapoka akasiyana siyana ehunyanzvi hwekubatanidza kweGemini Surchers Gare gare, Qiu et al [16] yakagadzirwa nzira itsva yeiyo synthesis yeGemini Surepants ine zvinyorwa zveCethls |
Tsvagurudzo pane gemini surfachers muChina yakatanga kunonoka; Muna 1999, Jianxi Zhao anobva kuFuzhou Yunivhesiti yakaita kuti idzore ongororo yekune dzimwe nyika pane gemini surapants uye yakakwezva kutarisisa kwakawanda ongororo dzekutsvaga muChina. Mushure meizvozvo, kutsvagisa pane gemini surfachinja muChina kwakatanga kubereka uye kuwanza mibairo inobereka. Mumakore achangopfuura, vaongorori vakavazvipira mukuvandudzwa kwetsva yeGemini yeGemini surapants uye kudzidza kwavo tsika yavo yefiremal. Panguva imwecheteyo, mashandiro eGemini surfectants akagadzirwa zvishoma nezvishoma muminda yekuruma uye antibacterial, kugadzirwa kwechikafu, kutsamwisa uye kusunungura zvinodhaka nekuchenesa zvinodhaka. Zvichienderana nekuti mapoka ehydrophilic mumaviri emamolecules ari kubhadharwa kana kuti kwete uye rudzi rwechiratidzo chavanotakura mumapoka anotevera: Cationic, anonic, nonitic uye amphoteric gemini surapants. Pakati pavo, cationic gemini surfachers anotumira quaternary ambomini maGemini Surepants ane Sulfonic
1.1 cationic gemini surapants
Cationic Gemini Surapants inogona kuburitsa zvimedu zvemvura mumvura mumvura, kunyanya Amonium uye Quaternary Apmonium Munyu Gemini surure. Cationic Gemini Surapants ane yakanaka biodegradability, yakasimba masimba emakemikari, yakaderera yekuparadzaniswa, kucheneswa, uye zvakare fungidziro, fungidziro, yeanosva, antistatic zvivakwa uye kupfava.
Quaternary Apmonium Munyu-yakavakirwa Gemini Surapants inowanzogadzirira kubva kune tertiary etines nekusagadzikana maitiro. Kune maviri mainini main innthetic nzira dzekutevera: imwe ndeyekutora Dibromo-yakatsiva alkanes uye imwe refu-ketani-alkyl dimetyl tertiary amines; Imwe yacho ndeyekutora-buternze-bromo-yakatsiva refu-keteni alkanes and n, n, n'-tetramethyl alkyl ethanol se solvent uye kupisa reflux. Nekudaro, Dibromo-yakatsiviwa Alkanes ari anodhura uye anowanzoiswa nenzira yechipiri, uye kuenzana kwekuita kunoratidzwa mumufananidzo 2.
1.2 Anonic Gemini Surapants
Anonic Gemini Surapants anogona kuburitsa hunganodzidzisa nehasha mumvura mhinduro, kunyanya sulfonates, sulfate saltlates and phosphate salts mhando gemini surfectors. Anonic surfaacts ane zvivakwa zviri nani senge decontamination, kupupurirwa, kupararira, kusvibiswa uye kushandiswa zvakanyanya sekudzivirira, vamiririri vanopenga, vanonyengera uye vanopararira.
1.2.1 Sulfonates
Sulfonate-yakavakirwa Biosurfaers ine zvakanakira mvura yakanaka yekunyorova, tembiriro remunyu, uye anozvinyudza, uye nemamiriro ekunze emazuva ese, uye maitiro ekugadzira. mutengo wakaderera. Li et al inthesized yeNew Dialalfonic Aculfonic acid surach
1.2.2 Sulfate Salts
Sulfate Ester Saltst Surfers Iyo zvakare ine yakanaka yekushambidza kushanda uye yekupinza kugona, kuita kwakagadzikana mumvura yakaoma, uye sulfate ester salts haina kwaakarerekera kana zvishoma alkaline mhinduro. Sezvinoratidzwa mumufananidzo 3, zuva dong et al vakashandisa lauric acid uye polyethyle glycol zvisungo, nekuwedzera kusuwa, nekushongedza sulfate ester typectant-ga12--12-ana.
1.2.3 Carboxylic acid salts
Carboxylate-based Gemini Surepancant inowanzo kuve nyoro, iri nyore biodeling zvivakwa, zvakanyanyisa kupararira, uye zvinyoro-nyoro mune mishonga yemishonga, zviumbwa, makemikari uye mamwe makemikari uye mamwe minda. Sumo yemapoka emagetsi mune car boxylate-based biosurffacacers inogona kusimudzira biodegradability yemamorekuru veSurfactant Mei et alnthesing carboxylate-based baryonic surfactant cgs-2 ine mapoka emagetsi uchishandisa dodecylamine, DibRoethane uye Succucinoc Anhydride seyakagadzirwa.
1.2.4 phosphato munyu
Phosphate ester Salt Type Gemini Surapants ane chimiro chakafanana chePhospholiclics uye vanowanzogadzira zvinhu zvakadai sekudzosera mortelles uye vesicles. Phosphate ester type yemunyu weGemini akashandiswa zvakanyanya sevamiriri veanosvitsa, uye midziyo yavo yakadzika echiMulesi Dzimwe estasphate geners dzinogona kuve anticancer, antitumor uye antibacterial, uye akawanda mishonga yakagadzirwa. Phosphathe ester Type Type Biosurfacers vane midziyo yekuuraya zvipuka uye inogona kushandiswa kwete chete seintilial uye zvipembenene asiwo semheni. Zheng et Alnthesis yeSynthesis yeSynthesis ester Salt Surachners Iyo molecular formula ye potassium phosphato munyu baryonic siractorant inoratidzwa mumufananidzo 4.
1.3 isiri-ionic gemini surapants
Pasonic gemini surapants haigone kusiyiswa mumhedzisiro mhinduro uye iripo mumanyorero fomu. Rudzi urwu rwebaryonic rave sarfactant rwave kushoma kusvika zvino, uye kune marudzi maviri, imwe shuga inobva uye imwe yacho inonwa ether uye phenol ether. Pasonic Gemini surepants haipo mune Ionic State mune mhinduro, saka vane kukanganiswa, havakanganisike nemagetsi akasimba, vane zvakajeka nemamwe marudzi eSurfacts, uye ane yakanaka yekubatana. Naizvozvo, surfalants is surfachers dzakasiyana-siyana dzakadai sekufungidzira kwakanaka, kuparadzaniswa, kuparadzaniswa, kune zvakashata, uye zvinogona kushandiswa zvakanyanya mune dzakasiyana siyana mishonga yekuuraya zvipuka uye mishonga yechipfuva. Sezvinoratidzwa mumufananidzo 5, muna 2004, Fitzgerald et al Synthesized polyoxythylene
02 Physicochemical Properties yeGemini Surepants
2.1 chiitiko che gemini surapants
Iyo yakapfava uye yakanyanya kutaurwa nzira yekuongorora iyo nzvimbo yemaseketa ndeyekuyera iyo nzvimbo yekupokana kwemhinduro dzawo. Mune musimboti, surfachants inoderedza kusawirirana kweiyo mhinduro neyekugadziridza gadziriro pamusoro (muganho) ndege (Mufananidzo 1 (C) 1 (C) (C) (C) (C) (C) (C) (C) (C) (C) (C) (C) (C) (C) (C) (C) (C). Iyo yakaoma micelle yekukasira Iyo baryonic surfactant molecule ine mapoka maviri ehydrophilic inobatsira kuti ichengetedze yakanaka mvura solubility uchiita marefu mahyrophobic marefu marefu. PaMvura / Mhepo Interface, Surfalants yakajairika yakarongwa zvakasununguka nekuda kwespeti Site kupokana uye nekudzikisira mhosva yemamorekuru, nekudaro ichinetsa kugona kwavo kuderedza nzvimbo yemvura. Mukupesana, mapoka ekubatanidza eGemini surepants akasungwa kuitira kuti kureba kwemapoka maviri anochengetwa mukati meiyo hydrophic mapoka evaridzi veHydrophil
2.2 Masangano magungano eGemini Surapants
Mumashoko okumvura, sekusangana kwemvura, sezvo mamorekuru anowedzera, ma moleculoles anowedzera pamusoro pemhinduro, ayo anodzora mamwe mamorekuru kuti atama kune iyo mhinduro yekugadzira micelles. Iko kusunganidzwa uko iyo iyo Surfactant inotanga kuumba micelles inonzi yakaoma micellocation (CMC). Sezvinoratidzwa mumufananidzo 9, mushure mekusangana kwakanyanya kupfuura CMC surfers Misiyano iri muMicelle Saizi, chimiro uye hydration ine maitiro akananga pane chikamu chehare uye rateological zvivakwa zvemhinduro, uye zvakare zvinotungamira kuchinja kweSolution viscoelasticity. Surfalachinja surfachants, yakadai seanonic surfacts Nekudaro, iyo yakakosha mamiriro eGemini surepancers inotungamira kune kuumbwa kweiyo micellx morgex morlex uye zvinhu zvemukati zvemukati mhinduro dzakasiyana zvakanyanya kubva kune avo vanowanzoitika surfactors. Iyo viscosity yemvura mhinduro dzeGemini dzinowedzera nekuwedzera kusungwa kweGemini Surepants, pamwe nekuti yakaumbwa mutsara micelles intertwine mune yewebhu-sewebhusaiti. Nekudaro, iyo viscosity yekugadzirisa inoderedza nekuwedzera kusimuka kwekuona surdent
03 Antimicrobial Properties yeGemini Surapants
Semhando yeiyo organic antimicrobial mumiririri weBaryonic Surfactant ndeyekuti anobatanidza mapoka ehutachiona emapuroteni uye nekuparadza microbial tishu kuti inhibit kana kuuraya microorganisms.
3.1 Antimicrobial Properties yeAnonic Gemini Surepants
Iyo antimicrobial zvivakwa zveAntimicrobial anionicsants inonyanya kutsanangurwa nemhando yeiyo antimicropili moietries yavanotakura mafoto avanotakura. Mumhinduro dzeColidal SEZVAKASHURE NEMAHARA uye MBETALYSECAIN SANGANO YEMAHARA Mapoka ehutachiona ehutachiona pane ino dense yekudzivirira inotsigira kukura kwehutachiona hwehutachiona.
Iyo Mechanism yehutachiona hwehutachiona hweAnonic surfers Iyo bacterial inhibition yeAnionic surfects inoenderana neyavo mhinduro system uye mapoka emukati, saka rudzi urwu rwemunhu wepachiratidzo anogona kuve mashoma. Rudzi urwu rwechiratidzo runofanirwa kuve uripo kune huwandu hwakaringana kuitira kuti siractant iripo mukona yega yega yehurongwa kuti ibudise microbilidal. Panguva imwecheteyo, rudzi urwu rwevaridzi vanodzvanya zvekunyepedzera uye zvinorehwa, izvo zvisingangoita kuti marara akakosha, asi zvakare zvinoumba kudzikisira kwenguva yakareba.
Semuenzaniso, Alkyl Sulfonate-based Biosurfafalanti yakashandiswa mumirauro wekiriniki. Alkyl Sulfonates, yakadai seBusulfani uye treosulfan, inobata zvirwere zvemizikiso, vachiita zvekubatanidza pakati peGuanine, uku kushandurwa uku hakugone kufananidzwa, zvichikonzera cellular kuverenga.
3.2 Antimicrobial Properties yeCatiic Gemini Surapants
Rudzi rukuru rwecationic gemini surapants dzakavandudzwa quaternary ambomoni type yemunyu weGemini surapants. Quaternary AMMonium Type Cateic Gemini Surapants ane mikana yakasimba yeAlkane maAblecuces Panguva imwecheteyo, vane mbiri dzakachengetedzwa nitrogen nicsorption yemamorekuru vechiratidzo, chinja chidimbu chemarara embira Mapoka eHydrophic akadzika mumapuroteni, achitungamira pakurasikirwa kweiyo enzyme chiitiko uye protein kuyananiswa, nekuda kwemhedzisiro yeaya maviri mhedzisiro, kugadzira iyo fungidziro ine yakasimba mabheti ane simba.
Nekudaro, kubva kune maonero ekutarisisa, idzi surfacton vane hemolytic chiitiko uye cytoticityity, uye kwenguva refu yekufona nenguva yezvisikwa zvemumvura uye biodegradation inogona kuwedzera hutachiona hwavo.
3.3 Antibacterial Properties ye nonsion gemini surapants
Parizvino pane mhando mbiri dzemhando dzisirioni dzegirini, imwe shuga inobva uye imwe yacho idoro ether uye phenol ether.
Iyo antibacterial mechanism ye svutugadzike-yakatorwa biosurffacacers inoenderana nehukama hwemamorekuru, uye surched surfact Kana iko kusungwa kweshuga kunoitika surachers vanosvika pane imwe nhanho, inochinja kufungidzira kweiyo menduru, inokanganisa kutakura kwevakadzi uye gasi kuchinjana, kukonzera kubuda kwemukati uye pakupedzisira kunotungamira kurufu rwebhakitiriya.
Iyo Antibacterial Mechanism yeiyo phenoil uye doro anonyanya kudhakwa vamiriri kuita pane cell wall kana menduru membrane uye enzarmes, kuvhiringidza mabasa ezvekuzvibata. Semuenzaniso, zvinodhaka zvemishonga ye dipherl ma dipherl uye nhaka yavo. Izvo zvakare zvakaitawo mitezo yemetabolic uye yekufema yeiyo enzymes mukati mebhakitiriya, iyo inobva yakundikana.
3.4 Antibacterial Properties yeAmphoteric Gemini Surapants
Amphoteric Gemini Surapants idzo kirasi yeSurfaers ine maviri macations vane chimiro chavo chemanyorerwo, uye kuratidzira zvinhu zvemukati zveanonic surfact Chishandiso chehutachiona cheButthion cheAmphoteric surfers
3.4.1 Antimicrobial Properties yeAmino Acid Gemini Surapants
Amino Acid mhando baryonic surfert Iyo inoyerwa yakapihwa siracant inokwezva kune zvisina kunaka kubhadharisa chikamu chehutachiona Iyo ine zvakakwanisika zvakanakira quaternary quaternary ambomini-gemini surapants: zviri nyore biodergradability, yakaderera hemolytic chiitiko, saka iri kugadzirwa kuti ishandiswe yayo uye munda wayo wekushandisa ari kuwedzera.
3.4.2 Antibacterial Properties yeasina-amino acid mhando gemini surapants
Iyo isiri-amino acid mhando amphoteric gemini surepants ine nzvimbo inoshandira molecular inosara ine ese asiri-onizable yakanaka uye isina kunaka nzvimbo dzekubhadhara. Iyo huru isina-amino acid mhando gemini surapants ndeye betane ,mizazoline, uye Amine oxide. Kutora mhando semuenzaniso, betane-mhando maAmphoterics vane masisitimu echiSornic uye ane masisitimu ecation. Iyo zvakare ine maitiro akanaka ekuwedzera nemamwe marudzi easurachers.
04 Mhedziso uye Outlook
Gemini Surapants ari kuwedzera kushandiswa muhupenyu nekuda kwechimiro chavo chakakosha, uye ivo vanoshandiswa zvakanyanya muminda yeanonamata antibacterial, kugadzirwa kwechikafu, kusunungurwa uye kusunungura zvinodhaka, kusunungura zvinodhaka nekuchenesa kwemaindasitiri. Nekuwedzera kwekuwedzera kwekuchengetedza zvakasikwa kuchengetedza, Gemini surapants inogadzirwa zvishoma nezvishoma mukushamwaridzana nekwavo kushamwaridzana uye multifuntional surfachan. Kutsvaga kwemberi paGemini Surepants kunogona kuitwa mune zvinotevera zvinhu: Kukudziridza matsva eGemini surapants ane zvimisikidzo uye mabasa, kunyanya kusimbisa kutsvagurudza nezve antibacterial uye antiviverrali; kuumbwa nevanowanzoitika surfers uye kushandisa zvakachipa uye zviri nyore zviripo zvekushandisa zvisina kugadzirwa zvekushandira zvakasarudzika zvakasarudzika gemini surapants.
Kutumira Nguva: Mar-25-2022